Endocrine Abstracts

Background: Visceral obesity has been associated with systemic oxidative stress, measured by oxidized LDL (oxLDL).Aim: Investigate circulating oxLDL levels in patients with visceral obesity, and its relationship with metabolic abnormalities found in visceral obesity.Methods: We evaluated blood pressure (BP), waist circumference (WC), fasting glucose, total cholesterol, LDL, HDL, triglycerides, ApoA1, ApoB, ApoCIII, Lp(a) and oxLDL ...

Prostate cancer (PCa) is an endocrine tumor that presents distinct metabolic features associated with neoplastic development, namely in the transition from the androgen-dependent to the androgen-independent phenotype that characterizes advanced stages of prostate cancer. Recently, we have found that LNCaP (androgen-responsive) and PC3 (androgen-nonresponsive) PCa cells present distinct glycolytic metabolism profiles in consequence of altered gene expression and/or activity of ...